As we age, our bodies produce less growth hormone (GH). This leads to many changes, including a reduction in muscle mass and strength, as well as an increase in fat. Both ipamorelin and sermorelin are substances that simulate GH release. They do this by targeting the same receptors (IGF-1) that release GH in response to natural stimuli such as exercise or fasting. Let’s take a look at exactly how these two substances operate.

How Ipamorelin Works

Ipamorelin is typically used as a treatment for short stature brought about by growth hormone deficiency (GHD). It mimics the effects of natural GH, increasing the amount produced by the pituitary gland and circulating in the bloodstream. It is delivered as an injection, either in the muscles or under the skin.

Ipamorelin is believed to stimulate the release of GH by binding to certain receptors in the pituitary gland. This fosters an increase in GH release, which in turn stimulates the liberation of insulin-like growth factor-1 (IGF-1) in the bloodstream. Ipamorelin may also affect metabolism, making it disintegrate fat faster so it can be used as energy.

How Sermorelin Works

Sermorelin triggers the release of GH from the pituitary gland, which is responsible for the assembly of many hormones, including growth hormone. Sermorelin also has a number of other uses, including as a treatment for type 2 diabetes, for patients who have formed insulin resistance over the years, and for treating other metabolic disorders.

Sermorelin is administered by injection and is typically used as part of a treatment for children who are deficient in GH because of a genetic disorder or a pituitary disorder.

Conclusion

All in all, both ipamorelin and sermorelin are useful substances that can be used to increase GH levels. They endow the release of natural GH in the body, which accounts for the growth of tissues, bones, and muscles. Additionally, it’s important that you understand the long-term effects of these treatments before embarking on any advanced treatment course.

Interest in GH peptide therapy? Connect with Tonik today.